Botox injections are an effective remedy for palmar hyperhidrosis (sweating of the palms of the hands) and relief can last many months. However, the pain involved in the administration of Botox to the hands along with occasional problems related to muscle weakness can make Botox a less desirable form of therapy for treating palmar hyperhidrosis. Although Botox is approved by the Federal Drug Administration in the United States for many medical uses, it is not yet approved for the treatment of excess perspiration. Physicians may use it to treat hyperhidrosis, but it is considered an “off-label” indication.
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